Wakarusa is an unincorporated community and census-designated place in Shawnee County, Kansas, United States. Wakarusa is 11 miles south of downtown Topeka. Wakarusa has a post office with ZIP code 66546. As of the 2010 census, its population was 260. Wakarusa is also the name of an unincorporated community in adjacent Douglas County, Kansas, 6.6�mi southwest of downtown Lawrence and the name of the township that includes Lawrence, Kansas.Wakarusa was founded in 1858.